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New Study Demonstrates Further Connection Between BPA Exposure And Development Of Breast Cancer

A new study has been published in the Proceeding of the National Academy of Sciences of the United States of America that demonstrates further evidence of a connection between exposure to bisphenol a (BPA) and the future development of breast cancer.  Here is a quick overview:

“This study assessed the effects of BPA on fetal mammary gland development in nonhuman primates. Pregnant rhesus monkeys were fed 400 μg of BPA per kg of body weight daily from gestational day 100 to term, which resulted in 0.68 ± 0.312 ng of unconjugated BPA per mL of maternal serum, a level comparable to that found in humans. At birth, the mammary glands of female offspring were removed for morphological analysis. Morphological parameters similar to those shown to be affected in rodents exposed prenatally to BPA were measured in whole-mounted glands; estrogen receptor (ER) α and β expression were assessed in paraffin sections. Student's t tests for equality of means were used to assess differences between exposed and unexposed groups. The density of mammary buds was significantly increased in BPA-exposed monkeys, and the overall development of their mammary gland was more advanced compared with unexposed monkeys. No significant differences were observed in ER expression. Altogether, gestational exposure to the estrogen-mimic BPA altered the developing mammary glands of female nonhuman primates in a comparable manner to that observed in rodents.”

So what does this all mean you ask?  The finding by this study continues to build upon previous studies that the exposing female fetus to BPA increases the risk of future development of breast cancer.  If you are pregnant you should consider not eating foods that come from containers (cans and bottles) that contain BPA.

Of course people like the American Chemistry Council will argue that these studies mean nothing about the safety of BPA because they were conducted on “monkeys” and “rodents” and not humans.   What they will not tell you is that is the way that studies like this must be conducted.  It is not ethical to conduct this type of studies on humans.  Unfortunately we have a long and somewhat recent history of horrible acts of secret and unethical medical research such as the Tuskegee Experiment and VD research in Guatemala.

The other interesting part of this growing story of a connection between BPA and breast cancer is the response by Komen.  At what point will Komen be forced to acknowledge the research on BPA and join the call to remove BPA from our food containers?  Or will Komen continue to demonstrate their inability to disagree with their sponsors and continues to chose money over science.

Finally we must ask again why the US Food and Drug Administration decided to take no action regarding BPA just a few weeks ago.  How much more information do you really need before you do what you are charged with doing and protect the public from BPA?  We are all watching and wondering when the FDA will stop being in the pocket of the American Chemistry Council and big plastics.

You can read the abstract of the study by following the link to PNAS website.  We close by thanking the following researches for conducting this study and sharing the information with the public:

Andrew P. Tharp, Maricel V. Maffini, Patricia A. Hunt, Catherine A. VandeVoort, Carlos Sonnenschein and Ana M. Soto